Wednesday, April 30, 2008

HYVET - High time we control Hypertension in elderly

HYVET - Control hypertension ( target of under 150/80 mm Hg in 80+ years old). This trial gave all us clinicians the definite answer to the question- should we control hypertension in elderly and its a definite "YES"

HYVET published in NEJM showed use of Indapamide (1.5 mg SR) with or without Perindopril (2mg or 4mg) resulted in a non significant reduction of 30% in fatal or non fatal stroke (defined primary end point) BUT showed a significant reduction in heart failure(64%), all cause mortality(21%), fatal stroke(39%), cardiovascular mortality due to stroke, MI, Heart failure by 34%.

Points to remember:
  1. Treat for Hypertension in elderly
  2. Remember to check for postural drop at every visit

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